A reviewing for profiling of highly degraded remains.
- Author:
Bai-Fang HE
1
;
Di-Dong LOU
Author Information
1. Department of forensic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China. healytomato@163.com
- Publication Type:Review
- MeSH:
Bone and Bones;
DNA/analysis*;
DNA Degradation, Necrotic;
DNA Fingerprinting/methods*;
Forensic Anthropology;
Genetic Markers;
Humans;
Polymerase Chain Reaction/methods*;
Polymorphism, Single Nucleotide;
Tandem Repeat Sequences;
Tooth/chemistry*
- From:
Journal of Forensic Medicine
2006;22(2):156-158
- CountryChina
- Language:Chinese
-
Abstract:
It's always a challenge to type from highly degraded biological remains. PCR-based STR genotyping is helpful and valuable for such degraded samples like bones, teeth et al, but the typing results are sometimes unstable or wrong. Here the methods for solving the problems and improving reproducibility are reviewed.
