Fibronectin immunohistochemical staining for diagnosing sudden death caused by viral myocarditis.
- Author:
Wen-Sheng LI
1
;
Qing-Jin GONG
;
Long-Wu LU
;
Yi-Jun ZHANG
;
Jian-Ding CHENG
Author Information
1. The Bureau of Public Security of Gongbei, Zhuhai 519020, China.
- Publication Type:Research Support, Non-U.S. Gov't
- MeSH:
Autopsy;
Death, Sudden/pathology*;
Diagnosis, Differential;
Fibronectins/metabolism*;
Humans;
Immunohistochemistry;
Myocarditis/virology*;
Myocardium/pathology*;
Staining and Labeling
- From:
Journal of Forensic Medicine
2006;22(2):84-85
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To study the value of Fibronectin(Fn) immunohistochemical staining for diagnosing slight viral myocarditis.
METHODS:The heart samples of human with myocarditis were studied by using LSAB immunohistochemical staining with anti-fibronectin antibody.
RESULTS:Dense deposition was found in the myocardium of human with myocarditis. Some Fn-positive cardiomyocytes were observed.
CONCLUSION:Slight degeneration of cardiomyocytes could be identified by Fn-LSAB immunohistochemical staining and Fn-deposition is one of the reliable marks for inflammation in the myocardium.
