Correlation between PMI and DNA degradation of costicartilage and dental pulp cells in human being.
- Author:
Ren LONG
1
;
Wei-ping WANG
;
Ping XIONG
Author Information
1. Department of Forensic Medicine, Nanhua University, Hengyang 421001, China.
- Publication Type:Journal Article
- MeSH:
Adolescent;
Adult;
Autopsy;
Cartilage/metabolism*;
DNA/metabolism*;
Dental Pulp/cytology*;
Female;
Forensic Pathology/methods*;
Humans;
Image Processing, Computer-Assisted/methods*;
Male;
Middle Aged;
Postmortem Changes;
Ribs/metabolism*;
Temperature;
Time Factors;
Young Adult
- From:
Journal of Forensic Medicine
2005;21(3):174-176
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To probe the correlation between the postmortem interval (PMI) and the DNA degradation of costicartilage and dental pulp cells in human being after death, and to seek a new method for estimating PMI.
METHODS:The image cytometry was used to measure the DNA degradation under different ambient temperatures (30-35 degrees C, 15-20 degrees C) in 0-15 days after death.
RESULTS:The average DNA content of two kinds of tissue was degradated with the prolongation of PMI. But there was a plateau period of 0-4 days for dental pulp cells of human being in 15-20 degrees C. There was a high negative correlativity P<0.01 between the average DNA content and PMI.
CONCLUSION:PMI could be estimated accurately according to the DNA degradation of costicartilage and dental pulp cells in human being after death.
