The application of telomere DNA in age estimation of forensic medicine.
- Author:
Hong-wei SUN
1
;
Cai-rong GAO
Author Information
1. School of Forensic Medicine, Shanxi Medical University, Taiyuan 030001, China. shwei2002nm@yahoo.com.cn
- Publication Type:Review
- MeSH:
Adolescent;
Adult;
Aging/physiology*;
Blotting, Southern/methods*;
Cell Division/physiology*;
DNA/analysis*;
Forensic Medicine/methods*;
Humans;
Polymorphism, Restriction Fragment Length;
Telomere/physiology*
- From:
Journal of Forensic Medicine
2005;21(2):155-158
- CountryChina
- Language:Chinese
-
Abstract:
Estimating tooth age and skeletal age are the two primary methods in age estimation of forensic medicine. But they are often impacted with geographical environment, nutrition, habitation and ethenologic differences, so the accuracy will be reduced, especially to the adult. With the study of telomere, it is certain that the length of the telomere DNA can reflect the cell division and represent the cell lifespan, and it has some pertinence to the age of the donor, so to measure the length of telomere DNA is a new and valuable method for age estimation in the forensic medicine.