Study of CTnI immunohistochemistry on acute myocardial infarction in rabbits.
- Author:
Jian-zhang JIA
1
;
Zi-qin ZHAO
;
Yun-ju GU
Author Information
1. Department of Forensic Medicine, Shanghai Medical College, Fudan University, Shanghai, China.
- Publication Type:Journal Article
- MeSH:
Animals;
Antibodies, Monoclonal;
Disease Models, Animal;
Female;
Immunohistochemistry;
Male;
Myocardial Infarction/metabolism*;
Myocardial Ischemia/pathology*;
Myocardium/pathology*;
Rabbits;
Sensitivity and Specificity;
Time Factors;
Troponin I/metabolism*
- From:
Journal of Forensic Medicine
2005;21(2):104-106
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To investigate the signification of CTnI in acute myocardial infarction.
METHODS:The model of myocardial infarction was established by ligating the left ventricle branch. Immunohistochemistry and image analysis were used to detect the change of CTnI in the model, and The sensitivity of immunohistochemistry and HE coloration were also compared.
RESULTS:The acute myocardial infarction tissue showed obvious depletion of CTnI, there was no characterization of myocardial infarction in HE coloration.
CONCLUSION:CTnI is sensitive to diagnosis of acute myocardial infarction.
