Application of the age-associated injure in mitochondrial DNA.
- Author:
Di-dong LOU
1
;
Chun-ying YU
;
Qing-en YANG
Author Information
1. Faculty of Forensic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China. loudidong@hotmail.com
- Publication Type:Review
- MeSH:
Aging/physiology*;
Base Pair Mismatch/genetics*;
DNA Damage/physiology*;
DNA Fragmentation/genetics*;
DNA, Mitochondrial/physiology*;
Gene Deletion;
Humans;
Polymerase Chain Reaction
- From:
Journal of Forensic Medicine
2004;20(4):253-255
- CountryChina
- Language:Chinese
-
Abstract:
Nowadays, the injury in human mitochondrial DNA (mtDNA) is well known to accumulate in various tissues with age. It's significant to further investigate and then apply it to estimation of the age at parenchymas.