Application of chi-square test and exact test in Hardy-Weinberg equilibrium testing.
- Author:
Dai-Xin HUANG
1
;
Qing-En YANG
Author Information
1. Faculty of Forensic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030,China. huangdaixin@hotmail.com
- Publication Type:Review
- MeSH:
Alleles;
Chi-Square Distribution;
Forensic Medicine;
Gene Frequency;
Genetics, Population/methods*;
Genotype;
Humans;
Likelihood Functions;
Models, Genetic;
Models, Statistical
- From:
Journal of Forensic Medicine
2004;20(2):116-119
- CountryChina
- Language:Chinese
-
Abstract:
This article review the application of chi-square test of various data handling methods and exact test in Hardy-Weinberg equilibrium testing of human genetic marker in population genetics. The importance of HWE-exact test in multiallelic system was emphasized, especially in the study of forensic VNTR and STR typing.
