The genetic polymorphism of 7 Y-STR loci and haplotype in Tibetan population.
- Author:
Dong ZHAO
1
;
Bao-jie WANG
;
Mei DING
Author Information
1. Department of forensic medicine, China Medical University, Shenyang 110001, China.
- Publication Type:Research Support, Non-U.S. Gov't
- MeSH:
Alleles;
China/ethnology*;
Chromosomes, Human, Y/genetics*;
Forensic Medicine;
Gene Frequency;
Genetic Markers;
Genetics, Population;
Haplotypes;
Humans;
Male;
Paternity;
Polymorphism, Genetic;
Tandem Repeat Sequences
- From:
Journal of Forensic Medicine
2004;20(2):88-91
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To investigate the genetic polymorphism of 7 Y-STR loci and haplotypes in Tibetan population.
METHODS:The DNA samples from 67 Tibetan men were analyzed by PCR and the denatured PAGE followed by silver staining.
RESULTS:25 alleles were identified for 6 loci including DYS393, DYS389 I, DYS19, DYS390, DYS389 II and DYS392, 22 alleles were identified for DYS385, the frequency distributions were between 0.0149-0.5075, the DP value distributions were between 0.5075-0.8991, the DP value of DYS 385 was the highest. 51 haplotypes were identified for the YH6 system which consisted of the 7 loci, the DP value of this system was 0.9887, the alleles for DYS393 and DYS389 II were few, it followed that perhaps Tibetan population had met with bottleneck event in their evolution process.
CONCLUSION:The 7 STR loci above belong to loci of high discriminating ability, the haplotypes are highly polymorphic.
