Expression of water channel protein 1 in the lung of the drown rat.
- Author:
Hua-zi HU
1
;
Chen YANG
;
Liao ZHI-GANG
Author Information
1. West China School of Preclinical and Forensic Medicine, Sichuan University, Chengdu 610041, China.
- Publication Type:Journal Article
- MeSH:
Animals;
Aquaporin 1;
Aquaporins/metabolism*;
Drowning/metabolism*;
Endothelial Cells/metabolism*;
Immunohistochemistry;
Lung/metabolism*;
Membrane Proteins/metabolism*;
Rats;
Rats, Sprague-Dawley
- From:
Journal of Forensic Medicine
2004;20(1):13-14
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To determine the expression of water channel 1 protein in the lung of drown rat and that of after death thrown into the water.
METHODS:Immunohistochemical method was used and the computer image analysis was conducted to detect the distribution of AQP1.
RESULTS:The positive expression of AQP1 was seen in the capillary endotheliocyte of the interstitial and around bronchi and in the alveolar endothelial cells. The value of intergrated optical density was statistical significant.
CONCLUSION:It suggests that AQP1 is one of sensitive signs to distinguish ante-mortem and postmortem immersion.
