Study on the solid dispersion system of dihydroartemisinine and application to the galenic form of suppository
- Author:
Ha Thi Hong Nguyen
- Publication Type:Journal Article
- Keywords:
dihydroartemisinine
- MeSH:
Sesquiterpenes;
Suppositories
- From:Pharmaceutical Journal
1999;282(10):18-20
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
The solid dispersion system (SDA) of dihydroartemisinine (DHA) with PEG 400, PEG 1540, PEG 4000, PEG 6000 and Tween 20, cremophor EL, PEG 400 stearate as cocarrier were prepared. the experimental results showed that the release rate of DHA from suppository base was greater than the semi-synthetic triglyceride base and the physico-mixture