Genetic polymorphism and the population difference of 7 Y-STR loci and haplotypes in Chinese Han and Japanese populations.
- Author:
Dong ZHAO
1
;
Bao-jie WANG
;
Mei DING
Author Information
1. Department of Forensic Medicine, China Medical University, Shenyang 110001, China.
- Publication Type:Research Support, Non-U.S. Gov't
- MeSH:
Asian People/genetics*;
China;
Chromosomes, Human, Y/genetics*;
Forensic Medicine;
Gene Frequency;
Genetics, Population;
Haplotypes/genetics*;
Humans;
Japan;
Male;
Microsatellite Repeats;
Paternity;
Polymorphism, Genetic
- From:
Journal of Forensic Medicine
2003;19(3):143-148
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To investigate the genetic polymorphism of 7 Y-STR loci and haplotypes and analyze their population difference.
METHODS:The DNA samples from 45 Chinese Han and 59 Japanese men were analyzed by PCR and the denatured PAGE followed by silver staining.
RESULTS:33 alleles were identified for 6 loci including DYS393, DYS389 I, DYS19, DYS390, DYS389 II and DYS392, 39 alleles were identified for DYS 385, the frequency distributions were between 0.0169-0.6444, the DP value distributions of them were between 0.5406-0.9579, the DP value of DYS 385 was the highest. With the comparison of data of the 7 loci, significant difference in genetics was observed between the two populations(P < 0.05). There were 95 haplotypes that consisted of the 7 loci, Chinese Han had 41 haplotypes, DP value 0.9960, Japanese population had 54 haplotypes, DP value 0.9965, no common haplotypes were found between them.
CONCLUSION:The 7 STR loci above belong to loci of high discriminating ability, the haplotypes are highly polymorphic and their ethical character is apparent.
