The unusual typing of short tandem repeats.
- Author:
De-jian LU
1
;
Yu-chuan CHEN
;
Hui-ling LU
Author Information
1. Department of Forensic Serology, Sun Yat-sen University of Medical Sciences, Guanzhou 510089.
- Publication Type:Review
- MeSH:
DNA Fingerprinting/methods*;
Forensic Medicine/methods*;
Gene Frequency;
Genotype;
Humans;
Polymerase Chain Reaction/methods*;
Polymorphism, Genetic;
Tandem Repeat Sequences/genetics*
- From:
Journal of Forensic Medicine
2002;18(2):118-123
- CountryChina
- Language:Chinese
-
Abstract:
Short tandem repeats (STRs) have been widely used in forensic sciences such as stain analysis and paternity testing. Although most of STR typing could give the reliable and clear results, some unusual typing have been observed in forensic practice. The anomalous typing could result from a lot of causes, including DNA genetic variation, poor quality or quantity of DNA template, different typing system or method, nonspecific reaction in PCR or anomalous electrophoresis migration. The unusual results may disturb the right interpretation of STR typing.
