The changes of electrocardiogram and serum cardiac troponin I at the early stage of crush injury in rats.
- Author:
Yu-chuan CHEN
1
;
Shui-ping LIU
;
Wei GUO
Author Information
1. Department of Forensic Pathology, Sun Yat-sen University of Medical Sciences, Guangzhou 510080.
- Publication Type:Journal Article
- MeSH:
Animals;
Crush Syndrome/physiopathology*;
Electrocardiography;
Extremities/injuries*;
Female;
Heart Injuries/physiopathology*;
Male;
Rats;
Rats, Sprague-Dawley;
Troponin I/blood*
- From:
Journal of Forensic Medicine
2002;18(2):76-77
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To observe the changes of electrocardiogram and serum cardiac troponin I at the early stage of severe crush injury in rats.
METHODS:Crush injury was produced in Sprague-Dawley rats. The changes of electrocardiogram were recorded with the standard II, the serum levels of cardiac troponin I were studied by automated chemiluminescence assay.
RESULTS:The ST segment elevated considerably after crush injury and lasted 24 h, the levels of serum cTnI were much higher than those of the control groupes after 6 h of injury.
CONCLUSION:Cardiomyocyte injury was induced in the early phase of crush injury.
