A study of genetic polymorphism of the STR loci D20S85 and D6S477 in Han population living in Wuhan.
- Author:
Hai-yan SONG
1
;
Rong-zhi YANG
;
Qing-en YANG
Author Information
1. Department of Forensic Biology, Tongji Medical College of Huazhong University of Science and Technology, Wuhan, Hubei, 430030. song.hy@263.net
- Publication Type:Journal Article
- MeSH:
Alleles;
Asian People/genetics*;
China;
Forensic Medicine;
Gene Frequency;
Humans;
Polymorphism, Genetic;
Tandem Repeat Sequences/genetics*
- From:
Journal of Forensic Medicine
2002;18(1):17-18
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:The genetic polymorphism of two STR loci, D20S85 and D6S477, were studied in 280 unrelated Chinese individuals in Wuhan.
METHODS:The PCR amplified products were analyzed by PAGE and silver staining.
RESULTS:10 and 9 alleles were observed in these two STR loci, and the discriminating power (DP) were 0.9085 and 0.9127 respectively. No deviations from Hardy-Weinberg equilibrium were found. The two STR loci had been successfully applied to individual identification and paternity testing.
CONCLUSION:The results demonstrated that the two loci were useful for forensic identification.