Immunohistochemical study with depletion of cardiac troponin T in rats on early myocardial ischaemia.
- Author:
Da-zhong DENG
1
;
Yu-Chuan CHEN
;
Bin-jie HU
Author Information
1. Department of Criminal Technique, Guangdong Police College, Guangzhou 510232. DDZEmail@163.net
- Publication Type:Journal Article
- MeSH:
Animals;
Female;
Forensic Medicine;
Image Processing, Computer-Assisted;
Immunohistochemistry;
Male;
Myocardial Ischemia/metabolism*;
Myocardium/metabolism*;
Rats;
Rats, Sprague-Dawley;
Troponin T/metabolism*
- From:
Journal of Forensic Medicine
2002;18(1):12-14
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To study the depletion of cardiac troponin T in Rats of early myocardial ischaemia.
METHODS:Immunohistochemical method (LSAB) was used and the depletion area of CTnT in myocardial ischaemia were measured by the computer image analysis.
RESULTS:There is obviously depletion of CTnT after 15 min in myocardial ischaemia of rats, the mean of CTnT depletion of myocardial ischaemic group is significant difference compared with that of the control group (P < 0.01), and the depletion area increased with the prolongagtion of ischaemic time.
CONCLUSION:The depletion of CTnT is one of sensitive signs of early myocardial ischaemia.
