Effect of nasal swell body on nasal airflow and Artemisia pollen deposition.
10.13201/j.issn.2096-7993.2023.07.006
- Author:
Ya ZHANG
1
;
Ruiping MA
1
;
Yusheng WANG
1
;
Jingliang DONG
2
;
Jingbin ZHANG
3
;
Zhenzhen HU
1
;
Feilun YANG
1
;
Minjie GONG
1
;
Miao LOU
4
;
Lin TIAN
5
;
Luyao ZHANG
1
;
Botao WANG
1
;
Yuping PENG
6
;
Guoxi ZHENG
1
Author Information
1. Department of Otolaryngology Head and Neck Surgery，the Second Affiliated Hospital of Xi'an Jiaotong University，Xi'an，710000，China.
2. Institute for Sustainable Industries & Liveable Cities，Victoria University，Australia.
3. Department of Medical Imaging，the Second Affiliated Hospital of Xi'an Jiaotong University.
4. Department of Otolaryngology Head and Neck Surgery，Shaanxi Provincial People's Hospital.
5. School of Engineering，RMIT University，Australia.
6. Department of Otolaryngology Head and Neck Surgery，Yulin No. 1 Hospital.
- Publication Type:Journal Article
- Keywords:
3D printing;
computational fluid dynamics;
discrete particle model;
nasal resistance;
nasal swell body
- MeSH:
Adult;
Humans;
Cross-Sectional Studies;
Nasal Cavity/surgery*;
Allergens;
Pollen;
Artemisia;
Hydrodynamics
- From:
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
2023;37(7):535-541
- CountryChina
- Language:Chinese
-
Abstract:
Objective:The nasal swell body（NSB） consists of the nasal septal cartilage, nasal bone, and swollen soft tissue, all of which are visible during endoscopic and imaging examinations. Although the function of the NSB remains uncertain, there is evidence to suggest that it plays a vital role in regulating nasal airflow and filtering inhaled air. Based on anatomical and histological evidence, it is hypothesized that the NSB is indispensable in these processes. This study aims to investigate the impact of NSB on nasal aerodynamics and the deposition of allergen particles under physiological conditions. Methods:The three-dimensional （3D） nasal models were reconstructed from computed tomography （CT） scans of the paranasal sinus and nasal cavity in 30 healthy adult volunteers from Northwest China, providing basis for the construction of models without NSB following virtual NSB-removal surgery. To analyze the distribution of airflow in the nasal cavity, nasal resistance, heating and humidification efficiency, and pollen particle deposition rate at various anatomical sites, we employed the computed fluid dynamics（CFD） method for numerical simulation and quantitative analysis. In addition, we created fully transparent segmented nasal cavity models through 3D printing, which were used to conduct bionic experiments to measure nasal resistance and allergen particle deposition. Results:①The average width and length of the NSB in healthy adults in Northwest China were （12.85±1.74） mm and （28.30±1.92） mm, respectively. ②After NSB removal, there was no significant change in total nasal resistance, and cross-sectional airflow velocity remained essentially unaltered except for a decrease in topical airflow velocity in the NSB plane. ③There was no discernible difference in the nasal heating and humidification function following the removal of the NSB; ④After NSB removal, the deposition fraction（DF） of Artemisia pollen in the nasal septum decreased, and the DFs post-and pre-NSB removal were（22.79±6.61）% vs （30.70±12.27）%, respectively; the DF in the lower airway increased, and the DFs post-and pre-NSB removal were（24.12±6.59）% vs （17.00±5.57）%, respectively. Conclusion:This study is the first to explore the effects of NSB on nasal airflow, heating and humidification, and allergen particle deposition in a healthy population. After NSB removal from the healthy nasal cavities: ①nasal airflow distribution was mildly altered while nasal resistance showed no significantly changed; ②nasal heating and humidification were not significantly changed; ③the nasal septum's ability to filter out Artemisia pollen was diminished, which could lead to increased deposition of Artemisia pollen in the lower airway.
