A comprehensive overview on the role of phytocompounds in human immunodeficiency virus treatment.
10.1016/j.joim.2023.05.001
- Author:
Chinmayee PRIYADARSANI MANDHATA
1
;
Chita RANJAN SAHOO
1
;
Rabindra NATH PADHY
2
Author Information
1. Central Research Laboratory, Institute of Medical Sciences and SUM Hospital, Siksha O Anusandhan Deemed to be University, Bhubaneswar, Odisha 751003, India.
2. Central Research Laboratory, Institute of Medical Sciences and SUM Hospital, Siksha O Anusandhan Deemed to be University, Bhubaneswar, Odisha 751003, India. Electronic address: rabindranathpadhy@soa.ac.in.
- Publication Type:Research Support, Non-U.S. Gov't
- Keywords:
Antiretroviral agents;
Antiretroviral therapy;
Gene therapy;
HIV;
Highly active;
Latent reservoir;
Phytochemicals;
Plant extracts
- MeSH:
Humans;
HIV;
HIV Infections/drug therapy*;
Anti-HIV Agents/therapeutic use*
- From:
Journal of Integrative Medicine
2023;21(4):332-353
- CountryChina
- Language:English
-
Abstract:
Acquired immune deficiency syndrome (AIDS) is a worldwide epidemic caused by human immunodeficiency virus (HIV) infection. Newer medicines for eliminating the viral reservoir and eradicating the virus are urgently needed. Attempts to locate relatively safe and non-toxic medications from natural resources are ongoing now. Natural-product-based antiviral candidates have been exploited to a limited extent. However, antiviral research is inadequate to counteract for the resistant patterns. Plant-derived bioactive compounds hold promise as powerful pharmacophore scaffolds, which have shown anti-HIV potential. This review focuses on a consideration of the virus, various possible HIV-controlling methods and the recent progress in alternative natural compounds with anti-HIV activity, with a particular emphasis on recent results from natural sources of anti-HIV agents. Please cite this article as: Mandhata CP, Sahoo CR, Padhy RN. A comprehensive overview on the role of phytocompounds in human immunodeficiency virus treatment. J Integr Med. 2023; 21(4):332-353.
