Research progress of extracorporeal cardiopulmonary resuscitation combined with therapeutic hypothermia on brain protection.
10.3760/cma.j.cn121430-20210823-01237
- Author:
Min YAO
1
;
Kerong ZHAI
2
;
Mingming LI
1
;
Yongnan LI
2
;
Zhaoming GE
1
Author Information
1. Department of Neurology, Lanzhou University Second Hospital, Lanzhou 730030, Gansu, China.
2. Department of Cardiac Surgery, Lanzhou University Second Hospital, Lanzhou 730030, Gansu, China.
- Publication Type:Journal Article
- MeSH:
Humans;
Brain;
Cardiopulmonary Resuscitation;
Brain Injuries;
Hypothermia, Induced;
Heart Arrest
- From:
Chinese Critical Care Medicine
2023;35(5):554-557
- CountryChina
- Language:Chinese
-
Abstract:
Compared with conventional cardiopulmonary resuscitation (CCPR), extracorporeal cardiopulmonary resuscitation (ECPR) can improve the survival rate of patients with cardiac arrest, and reduce the risk of reperfusion injury. However, it is still difficult to avoid the risk of secondary brain damage. Low temperature management has good neuroprotective potential for ECPR patients, which minimizes brain damage. However, unlike CCPR, ECPR has no clear prognostic indicator. The relationship between ECPR combined with hypothermia management-related treatment measure and neurological prognosis is not clear. This article reviews the effect of ECPR combined with different therapeutic hypothermia on brain protection and provides a reference for the prevention and treatment of neurological injury in patients with ECPR.
