YME1L overexpression exerts pro-tumorigenic activity in glioma by promoting Gαi1 expression and Akt activation.

Author: Fang LIU ¹ ; Gang CHEN ² ; Li-Na ZHOU ³ ; Yin WANG ⁴ ; Zhi-Qing ZHANG ⁴ ; Xihu QIN ⁵ ; Cong CAO ⁴
Author Information

1. Department of Neurosurgery, The Affiliated Changzhou No.2 People's Hospital of Nanjing Medical University, Changzhou 213004, China.
2. Department of Neurosurgery, The First Affiliated Hospital of Soochow University, Suzhou 215006, China.
3. Department of Radiotherapy and Oncology, Affiliated Kunshan Hospital of Jiangsu University, Suzhou 215300, China.
4. Department of Neurology and Clinical Research Center of Neurological Disease, The Second Affiliated Hospital of Soochow University, Suzhou 215004, China.
5. Department of General surgery, The Affiliated Changzhou No.2 People's Hospital of Nanjing Medical University, Changzhou 213004, China.
Publication Type:Research Support, Non-U.S. Gov't
MeSH: Humans; Brain Neoplasms/metabolism*; Cell Line, Tumor; Cell Proliferation; Gene Expression Regulation, Neoplastic; Glioma/metabolism*; Proto-Oncogene Proteins c-akt/metabolism*; Signal Transduction; ATPases Associated with Diverse Cellular Activities/metabolism*; Mitochondrial Proteins/metabolism*; GTP-Binding Protein alpha Subunits/metabolism*
From: Protein & Cell 2023;14(3):223-229
CountryChina
Language:English