Suppression of USP8 sensitizes cells to ferroptosis via SQSTM1/p62-mediated ferritinophagy.

Author: Lihong LIU ¹ ; Birong ZHENG ¹ ; Manhui LUO ¹ ; Jie DU ¹ ; Fang YANG ² ; Chuanxin HUANG ² ; Zengyi MA ³ ; Chunmei LI ¹ ; Deyin GUO ¹ ; Hong PENG ¹
Author Information

1. MOE Key Laboratory of Tropical Disease Control, Centre for Infection and Immunity Study (CIIS), School of Medicine, Sun Yat-sen University, Shenzhen 510275, China.
2. Shanghai Institute of Immunology and Department of Immunology and Microbiology, Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education, Faculty of Basic Medicine, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.
3. Department of Neurosurgery, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai 200433, China.
Publication Type:Research Support, Non-U.S. Gov't
MeSH: Apoptosis; Autophagy; Ferroptosis; Iron/metabolism*; Sequestosome-1 Protein/metabolism*; Ubiquitin-Specific Proteases/metabolism*
From: Protein & Cell 2023;14(3):230-234
CountryChina
Language:English