Cerebral ischemic injury after transcatheter aortic valve replacement in patients with pure aortic regurgitation.
- Author:
Xianbao LIU
1
;
Hanyi DAI
1
;
Jiaqi FAN
1
;
Dao ZHOU
1
;
Gangjie ZHU
1
;
Abuduwufuer YIDILISI
1
;
Jun CHEN
1
;
Yeming XU
1
;
Lihan WANG
1
;
Jian'an WANG
2
Author Information
- Publication Type:Journal Article
- MeSH: Humans; Transcatheter Aortic Valve Replacement; Aortic Valve Insufficiency; Diffusion Magnetic Resonance Imaging; Aortic Valve Stenosis; Stroke
- From: Journal of Zhejiang University. Science. B 2023;24(6):530-538
- CountryChina
- Language:English
- Abstract: Considering the surgical risk stratification for patients with severe calcific aortic stenosis (AS), transcatheter aortic valve replacement (TAVR) is a reliable alternative to surgical aortic valve replacement (SAVR) (Fan et al., 2020, 2021; Lee et al., 2021). Despite the favorable clinical benefits of TAVR, stroke remains a dreaded perioperative complication (Auffret et al., 2016; Kapadia et al., 2016; Kleiman et al., 2016; Huded et al., 2019). Ischemic overt stroke, identified in 1.4% to 4.3% of patients in TAVR clinical practice, has been associated with prolonged disability and increased mortality (Auffret et al., 2016; Kapadia et al., 2016; Levi et al., 2022). The prevalence of hyperintensity cerebral ischemic lesions detected by diffusion-weighted magnetic resonance imaging (DW-MRI) was reported to be about 80%, which is associated with impaired neurocognitive function and vascular dementia (Vermeer et al., 2003; Barber et al., 2008; Kahlert et al., 2010).
