Research progress on animal models of contrast-induced acute kidney injury.
10.11817/j.issn.1672-7347.2023.220608
- Author:
Ke DENG
1
;
Mingxin PEI
2
;
Yanling CHEN
3
Author Information
1. Department of Pathophysiology, Zhuhai Campus of Zunyi Medical University, Zhuhai Guangdong 519041, China. 3072342434@qq.com.
2. Department of Pathophysiology, Zhuhai Campus of Zunyi Medical University, Zhuhai Guangdong 519041, China.
3. Department of Pathophysiology, Zhuhai Campus of Zunyi Medical University, Zhuhai Guangdong 519041, China. 546475534@qq.com.
- Publication Type:Journal Article
- Keywords:
animal models;
contrast-induced acute kidney injury;
renal impairment
- MeSH:
Animals;
Acute Kidney Injury/chemically induced*;
Contrast Media/adverse effects*;
Models, Animal
- From:
Journal of Central South University(Medical Sciences)
2023;48(4):594-600
- CountryChina
- Language:English
-
Abstract:
Contrast-induced acute kidney injury (CI-AKI) refers to acute kidney injury that occurs after intravascular contrast media is applied. It is the third most common cause for acute renal failure in hospitalized patients and can cause severe renal impairment and adverse cardiovascular outcomes. In severe cases, it can even lead to the death of the patient. Due to its complicated pathogenesis, the pathogenesis of CI-AKI has not yet been elucidated. Therefore, it is of great significance to further study the pathogenesis for the prevention of CI-AKI. Moreover, a good animal model of CI-AKI is an important tool for in-depth research on the pathogenesis of acute kidney injury induced by contrast agents.
