Simulation Results and Analysis of Electric Field Distribution in Myocardial Tissue under Circular Electrode Electric Pulse Ablation.
10.3969/j.issn.1671-7104.2023.03.002
- Author:
Wencai WANG
1
;
Qunshan WANG
2
;
Binfeng MO
2
;
Jinhai NIU
1
Author Information
1. School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, 200240.
2. Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200092.
- Publication Type:Journal Article
- Keywords:
COMSOL simulation;
electric field distribution;
electric pulse ablation;
multi-electrode;
myocardial tissue
- MeSH:
Humans;
Heart Rate;
Atrial Fibrillation/surgery*;
Electrodes;
Catheter Ablation;
Electricity
- From:
Chinese Journal of Medical Instrumentation
2023;47(3):242-246
- CountryChina
- Language:Chinese
-
Abstract:
As a new energy source for atrial fibrillation ablation, electric pulse ablation has higher tissue selectivity and biosafety, so it has a great application prospect. At present, there is very limited research on multi-electrode simulated ablation of histological electrical pulse. In this study, a circular multi-electrode ablation model of pulmonary vein will be built on COMSOL5.5 platform for simulation research. The results show that when the voltage amplitude reaches about 900 V, it can make some positions achieve transmural ablation, and the depth of continuous ablation area formed can reach 3 mm when the voltage amplitude reaches 1 200 V. When the distance between catheter electrode and myocardial tissue is increased to 2 mm, a voltage of at least 2 000 V is required to make the depth of continuous ablation area reach 3 mm. Through the simulation of electric pulse ablation with ring electrode, the research results of this project can provide reference for the voltage selection in the clinical application of electric pulse ablation.
