Application of PET-LINAC in Biology-guided Radiotherapy.
10.3969/j.issn.1671-7104.2023.03.001
- Author:
Xin YANG
1
;
Wei ZHAO
2
;
Xinzhi TIAN
3
;
Jun CAI
4
;
Siwei XIE
5
;
Qi LIU
5
;
Hao PENG
5
;
Qiyu PENG
5
Author Information
1. Department of Oncology, The Second Xiangya Hospital of Central South University, Changsha, 410011.
2. School of Physics, Beihang University, Beijing, 102206.
3. X-Precise(Beijing) Medical Technology Co. Ltd., Beijing, 100176.
4. Suzhou magAssist Medical Technology Co. Ltd., Suzhou, 215000.
5. Institute of Biomedical Engineering, Shenzhen Bay Laboratory, Shenzhen, 518067.
- Publication Type:Journal Article
- Keywords:
LINAC;
PET;
biology-guided radiotherapy
- MeSH:
Positron Emission Tomography Computed Tomography;
Radiotherapy Planning, Computer-Assisted/methods*;
Algorithms;
Particle Accelerators;
Biology;
Radiotherapy, Image-Guided/methods*;
Radiotherapy Dosage
- From:
Chinese Journal of Medical Instrumentation
2023;47(3):237-241
- CountryChina
- Language:Chinese
-
Abstract:
Biology-guided radiotherapy (BgRT) is a novel technique of external beam radiotherapy, combining positron emission tomography-computed tomography (PET-CT) with a linear accelerator (LINAC). The key innovation is to utilize PET signals from tracers in tumor tissues for real-time tracking and guiding beamlets. Compared with a traditional LINAC system, a BgRT system is more complex in hardware design, software algorithm, system integration and clinical workflow. RefleXion Medical has developed the world's first BgRT system. Nevertheless, its actively advertised function, PET-guided radiotherapy, is still in the research and development phase. In this review study, we presented a number of issues related to BgRT, including its technical advantages and potential challenges.
