Advances in Molecular Subtyping, Characteristics and Therapeutic Strategies of
Small Cell Lung Cancer.
10.3779/j.issn.1009-3419.2023.106.08
- Author:
Yang WU
1
;
Jing ZHAO
2
;
Mengzhao WANG
2
Author Information
1. School of Medicine, Tsinghua University, Beijing 100084, China.
2. Department of Pulmonary and Critical Care Medicine, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100730, China.
- Publication Type:Journal Article
- Keywords:
Clinical characteristic;
Lung neoplasms;
Molecular subtype;
Treatment
- MeSH:
Animals;
Small Cell Lung Carcinoma/therapy*;
Lung Neoplasms/therapy*;
Immunotherapy;
Prognosis
- From:
Chinese Journal of Lung Cancer
2023;26(4):303-309
- CountryChina
- Language:Chinese
-
Abstract:
Small cell lung cancer (SCLC) is a malignant tumor with remarkable proliferative and invasive ability, which has very poor clinical prognosis due to lack of effective treatments. In recent years, researches on cells, animal models and tumor samples have promoted the identification of molecular subtypes of SCLC, discovered unique biological and clinical characteristics, and proposed potential specific therapeutic targets for different subtypes. This will encourage the development of more accurate therapeutic strategies towards SCLC, with a view to improving the prognosis of the patients. This article will review the current SCLC molecular subtypes, focus on the clinical characteristics and therapeutic strategies of different SCLC subtypes, and propose reasonable suggestions for the future treatment of SCLC.
.
