Research progress on long-term developmental outcomes of offspring of pregnant women with systemic lupus erythematosus.
10.7499/j.issn.1008-8830.2211036
- Author:
Shu-Ming SHAO
1
;
Yi-Min ZHANG
1
;
Xiao-Rui ZHANG
1
Author Information
1. Department of Pediatrics, Peking University People's Hospital, Beijing 100044, China.
- Publication Type:Journal Article
- Keywords:
Long-term outcome;
Offspring;
Pregnancy;
Systemic lupus erythematosus
- MeSH:
Pregnancy;
Humans;
Female;
Infant, Newborn;
Pregnancy Outcome/epidemiology*;
Pregnant Women;
Pregnancy Complications/epidemiology*;
Premature Birth/etiology*;
Lupus Erythematosus, Systemic
- From:
Chinese Journal of Contemporary Pediatrics
2023;25(4):415-419
- CountryChina
- Language:Chinese
-
Abstract:
Systemic lupus erythematosus (SLE) is an autoimmune connective tissue disease that affects multiple organs and systems. It is more common in women of childbearing age. Compared with the general population, pregnant women with SLE are at a significantly increased risk of adverse perinatal outcomes such as preterm birth and intrauterine growth restriction. In addition, the offspring of SLE patients may also be adversely affected by in utero exposure to maternal autoantibodies, cytokines, and drugs. This article summarizes the long-term developmental outcomes of offspring of pregnant women with SLE in terms of the blood system, circulatory system, nervous system, and immune system.
