Research Progresses of Tri-Allelic Patterns in Autosomal STR in Forensic DNA Analysis.
10.12116/j.issn.1004-5619.2023.530210
- Author:
Xiao-Yan MA
1
;
Hong-Yu SUN
1
;
Qing LI
2
Author Information
1. Faculty of Forensic Medicine, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou 510089, China.
2. Forensic Identification Institute, the Third Affiliated Hospital of Guangzhou Medical University, Guangzhou 510150, China.
- Publication Type:Journal Article
- Keywords:
DNA;
autosome;
forensic genetics;
review;
short tandem repeats;
tri-allelic pattern
- MeSH:
Alleles;
DNA/genetics*;
Forensic Medicine;
Gene Frequency;
Microsatellite Repeats;
Humans
- From:
Journal of Forensic Medicine
2023;39(3):240-246
- CountryChina
- Language:English
-
Abstract:
Tri-allelic pattern in autosomal STR is a common abnormal typing phenomenon in forensic DNA analysis, which brings difficulties and uncertainties to the evaluation of the evidence weight in actual cases. This paper reviews the types, formation mechanism, occurrence frequency, genetic pattern and quantitative evaluation of evidence of the tri-allelic pattern in autosomal STR in forensic DNA analysis. This paper mainly explains the formation mechanism and genetic patterns based on different types of tri-allelic pattern. This paper also discusses the determination of tri-allelic pattern and the quantitative method of evidence evaluation in paternity testing and individual identification. This paper aims to provide references for scientific and standardized analysis of this abnormal typing phenomenon in forensic DNA analysis.
