Processing Magnoliae Officinalis Cortex with ginger juice: process optimization based on AHP-CRITIC weighting method and composition changes after processing.
10.19540/j.cnki.cjcmm.20230424.302
- Author:
Yu-Fang QI
1
;
Xing-Chen FAN
1
;
Si-Chen WANG
1
;
Yu-An SU
1
;
Ke-Wei ZHANG
1
;
Chun-Qin MAO
1
;
Tu-Lin LU
1
Author Information
1. School of Pharmacy, Nanjing University of Chinese Medicine Nanjing 210023, China.
- Publication Type:Journal Article
- Keywords:
AHP-CRITIC weighting method;
Box-Behnken response surface methodology;
Magnoliae Officinalis Cortex;
composition change;
content determination;
process optimization;
processed with ginger juice
- MeSH:
Ginger;
Magnolia/chemistry*;
Drugs, Chinese Herbal/chemistry*;
Biphenyl Compounds/chemistry*;
Lignans/chemistry*
- From:
China Journal of Chinese Materia Medica
2023;48(14):3806-3814
- CountryChina
- Language:Chinese
-
Abstract:
The weight coefficients of appearance traits, extract yield of standard decoction, and total content of honokiol and magnolol were determined by analytic hierarchy process(AHP), criteria importance though intercrieria correlation(CRITIC), and AHP-CRITIC weighting method, and the comprehensive scores were calculated. The effects of ginger juice dosage, moistening time, proces-sing temperature, and processing time on the quality of Magnoliae Officinalis Cortex(MOC) were investigated, and Box-Behnken design was employed to optimize the process parameters. To reveal the processing mechanism, MOC, ginger juice-processed Magnoliae Officinalis Cortex(GMOC), and water-processed Magnoliae Officinalis Cortex(WMOC) were compared. The results showed that the weight coefficients of the appearance traits, extract yield of standard decoction, and total content of honokiol and magnolol determined by AHP-CRITIC weighting method were 0.134, 0.287, and 0.579, respectively. The optimal processing parameters of GMOC were ginger juice dosage of 8%, moistening time of 120 min, and processing at 100 ℃ for 7 min. The content of syringoside and magnolflorine in MOC decreased after processing, and the content of honokiol and magnolol followed the trend of GMOC>MOC>WMOC, which suggested that the change in clinical efficacy of MOC after processing was associated with the changes of chemical composition. The optimized processing technology is stable and feasible and provides references for the modern production and processing of MOC.
