A new dihydrochalcone from Humulus scandens.
10.19540/j.cnki.cjcmm.20221231.201
- Author:
Yuan-Ning WU
1
;
Biao SUN
1
;
Jun-Ya WANG
1
;
De-Zhi WANG
1
;
Min SONG
1
;
Xiao-Qi ZHANG
2
Author Information
1. Guangdong Engineering Research Center for Modernization of Traditional Chinese Medicine, Jinan University Guangzhou 510632, China.
2. Guangdong Engineering Research Center for Modernization of Traditional Chinese Medicine, Jinan University Guangzhou 510632, China NMPA Key Laboratory for Quality Evaluation of Traditional Chinese Medicine,Jinan University Guangzhou 510632, China.
- Publication Type:Journal Article
- Keywords:
Humulus scandens;
Moraceae;
chemical constituent;
flavonoid
- MeSH:
Humulus;
Chalcones;
Indoles;
Drugs, Chinese Herbal/chemistry*
- From:
China Journal of Chinese Materia Medica
2023;48(7):1885-1891
- CountryChina
- Language:Chinese
-
Abstract:
To study the chemical constituents from the stems and leaves of Humulus scandens, this study isolated thirteen compounds by different chromatographic methods including silica gel column, ODS, Sephadex LH-20 and preparative HPLC. Based on comprehensive analysis, the chemical structures were elucidated and identified as citrunohin A(1), chrysosplenetin(2), casticin(3), neoechinulin A(4), ethyl 1H-indole-3-carboxylate(5), 3-hydroxyacetyl-indole(6),(1H-indol-3-yl) oxoacetamide(7), inonotusic acid(8), arteannuin B(9), xanthotoxol(10), α-tocopherol quinone(11), eicosanyl-trans-p-coumarate(12), and 9-oxo-(10E,12E)-octadecadienoic acid(13). Among them, compound 1 was a new dihydrochalcone, and the other compounds were obtained from H. scandens for the first time.
