Quality analysis of Rosae Radix et Rhizoma.
10.19540/j.cnki.cjcmm.20230322.201
- Author:
Hai-Hui LIU
1
;
Chen-Na LU
1
;
Xuan-Xuan ZHU
1
;
Lu BAI
2
;
Li-Mei LIN
3
;
Qian-Wen CHEN
1
;
Wei-Hong FENG
1
;
Duan-Fang LIAO
3
;
Chun LI
1
Author Information
1. Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences Beijing 100700, China.
2. Qianjin Pharmaceutical Co., Ltd.,Zhuzhou 412007, China.
3. Hunan University of Chinese Medical Sciences Changsha 410208, China.
- Publication Type:Journal Article
- Keywords:
Rosae Radix et Rhizoma;
content determination;
extract;
fingerprint;
thin-layer chromatography
- MeSH:
Drugs, Chinese Herbal/chemistry*;
Rhizome/chemistry*;
Plant Roots/chemistry*;
Plants, Medicinal;
Quality Control
- From:
China Journal of Chinese Materia Medica
2023;48(10):2781-2791
- CountryChina
- Language:Chinese
-
Abstract:
Rosae Radix et Rhizoma is a herbal medicine in a variety of famous Chinese patent medicines, while the quality standard for this medicine remains to be developed due to the insufficient research on the quality of Rosae Radix et Rhizoma from different sources. Therefore, this study comprehensively analyzed the components in Rosae Radix et Rhizoma of different sources from the aspects of extract, component category content, identification based on thin-lay chromatography, active component content determination, and fingerprint, so as to improve the quality control. The results showed that the content of chemical components varied in the samples of different sources, while there was little difference in the chemical composition among the samples. The content of components in the roots of Rosa laevigata was higher than that in the other two species, and the content of components in the roots was higher than that in the stems. The fingerprints of triterpenoids and non-triterpenoids were established, and the content of five main triterpenoids including multiflorin, rosamultin, myrianthic acid, rosolic acid, and tormentic acid in Rosae Radix et Rhizoma was determined. The results were consistent with those of major component categories. In conclusion, the quality of Rosae Radix et Rhizoma is associated with the plant species, producing area, and medicinal parts. The method established in this study lays a foundation for improving the quality standard of Rosae Radix et Rhizoma and provides data support for the rational use of the stem.
