Relationship between immune regulation and structure of polysaccharides.
10.19540/j.cnki.cjcmm.20221220.601
- Author:
Nuo CHEN
1
;
Wen-Jie XI
1
;
Mei-Fen HU
1
;
Xing-Ye WEI
1
;
Ping XIAO
1
;
Jin-Ao DUAN
1
Author Information
1. Medicine Jiangsu Key Laboratory for High Technology Research of TCM Formulae, National and Local Collaborative Engineering Center of Chinese Medicinal Resources Industrialization and Formulae Innovative, Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization , Nanjing University of Chinese Medicine Nanjing 210023, China.
- Publication Type:Journal Article
- Keywords:
advanced conformation;
chemical modification;
immune regulation;
polysaccharide structure
- MeSH:
Monosaccharides/chemistry*;
Structure-Activity Relationship;
Molecular Weight;
Antioxidants/pharmacology*;
Polysaccharides/chemistry*
- From:
China Journal of Chinese Materia Medica
2023;48(10):2667-2678
- CountryChina
- Language:Chinese
-
Abstract:
Polysaccharides have significant immunomodulatory activity and have good development value in food and medicine fields. At present, there are many studies on the chemical structure and immune activity of polysaccharides, but the relationship between them of polysaccharides has not been fully explained, which limits the further development and utilization of polysaccharide resources. The immune activity of polysaccharides is closely related to their own structure. This paper systematically summarized the relationship between the relative molecular weight, monosaccharide composition, glycosidic bond types, chemical modification, and advanced conformation of polysaccharides and the immune regulation, aiming to provide references for the profound study of polysaccharide structure-activity relationship and utilization of polysaccharides.
