Research progress of Shegan Mahuang Decoction and predictive analysis on its Q-markers.
10.19540/j.cnki.cjcmm.20230302.201
- Author:
Qiu-Hui LI
1
;
Xiao-Xiao SHAN
2
;
Wei-Dong YE
1
;
Xun-Yan YIN
1
;
Ya-Mei YUAN
1
;
Xiang-Ming FANG
1
Author Information
1. School of Traditional Chinese Medicine, Anhui University of Chinese Medicine Hefei 230012, China.
2. School of Pharmacy, Anhui University of Chinese Medicine Hefei 230012, China.
- Publication Type:Journal Article
- Keywords:
Shegan Mahuang Decoction;
clinical application;
history;
mechanism;
quality markers
- MeSH:
Humans;
Ephedra sinica;
Drugs, Chinese Herbal/pharmacology*;
Asthma/drug therapy*;
Lung;
Cough/drug therapy*
- From:
China Journal of Chinese Materia Medica
2023;48(8):2068-2076
- CountryChina
- Language:Chinese
-
Abstract:
Shegan Mahuang Decoction has been used in clinical practice for thousands of years, and is a classical formula for treating asthma and other respiratory diseases, with the effects of ventilating lung, dispersing cold, and relieving cough and asthma. This paper summarized the history, clinical application and mechanism of Shegan Mahuang Decoction, and predicted its quality markers(Q-markers) based on the "five principles" of Q-markers. The results suggested that irisflorentin, tectoridin, tectorigenin, irigenin, ephedrine, pseudoephedrine, asarinin, methyleugenol, shionone, epifriedelanol, tussilagone, 6-gingerol, trigonelline, cavidine, schizandrin, and schizandrin B could be used as Q-markers of Shegan Mahuang Decoction, which provided a basis for the quality control and subsequent research and development of Shegan Mahuang Decoction.
