Research progress of Codonopsis Radix and prediction of its Q-markers.
10.19540/j.cnki.cjcmm.20221231.202
- Author:
Xiao-Yan LAN
1
;
Li ZHOU
1
;
Xiang LI
1
;
Rui-Bin BAI
1
;
Yi YU
2
;
Cong-Kui TIAN
3
;
Li-Ping KANG
1
Author Information
1. State Key Laboratory Breeding Base of Dao-di Herbs, National Resource Center for Chinese Materia Medica,China Academy of Chinese Medical Sciences Beijing 100700, China.
2. Infinitus (China) Co.Ltd. Guangzhou 510663, China.
3. Wuling Mountain Institute of Natural Medicine, Hubei Minzu University Enshi 445000, China.
- Publication Type:Journal Article
- Keywords:
Codonopsis Radix;
chemical constituents;
pharmacological activity;
quality control;
quality markers(Q-markers)
- MeSH:
Drugs, Chinese Herbal;
Codonopsis;
Alkaloids;
Medicine, Traditional;
Plant Roots
- From:
China Journal of Chinese Materia Medica
2023;48(8):2020-2040
- CountryChina
- Language:Chinese
-
Abstract:
Codonopsis Radix is a traditional tonic medicine commonly used in China, which has the effects of strengthening the spleen and tonifying the lung, as well as nourishing blood and engendering liquid. The chemical constituents of Codonopsis species are mainly polyacetylenes, alkaloids, phenylpropanoids, lignans, terpenoids and saponins, flavonoids, steroids, organic acids, saccharides, and so on. Modern pharmacological studies showed that Codonopsis Radix also has a variety of pharmacological effects such as enhancing body immunity, protecting gastrointestinal mucosa and resisting ulcers, promoting hematopoietic function, regulating blood sugar, and delaying aging. In this paper, the chemical constituents of Codonopsis species and the pharmacological effects of Codonopsis Radix were summarized, and on this basis, the quality markers of Codonopsis Radix were analyzed. It was predicted that lobetyolin, tangshenoside I, codonopyrrolidium A, and the oligosaccharides were the possible Q-markers of Codonopsis Radix. This paper will provide scientific references for the quality evaluation and profound research and the development of Codonopsis Radix.
