Chemical constituents of diterpenoids from Boswellia carterii.
10.19540/j.cnki.cjcmm.20230202.201
- Author:
Rong-Ye WANG
1
;
Hui XIA
1
;
Yong-Xiang WANG
1
;
Hao HUANG
1
;
Bo-Kai WANG
1
;
Meng DU
1
;
Yue-Lin SONG
2
;
Yun-Fang ZHAO
2
;
Jiao ZHENG
2
;
Hui-Xia HUO
2
;
Jun LI
3
Author Information
1. School of Chinese Materia Medica, Beijing University of Chinese Medicine Beijing 100029, China.
2. Modern Research Center for Traditional Chinese Medicine, Beijing Research Institute of Chinese Medicine,Beijing University of Chinese Medicine Beijing 100029, China.
3. School of Chinese Materia Medica, Beijing University of Chinese Medicine Beijing 100029, China Modern Research Center for Traditional Chinese Medicine, Beijing Research Institute of Chinese Medicine,Beijing University of Chinese Medicine Beijing 100029, China.
- Publication Type:Journal Article
- Keywords:
Boswellia carterii;
cembrane;
chemical constituents;
diterpenoids;
vanilline
- MeSH:
Molecular Structure;
Boswellia/chemistry*;
Diterpenes/chemistry*;
Mass Spectrometry
- From:
China Journal of Chinese Materia Medica
2023;48(9):2464-2470
- CountryChina
- Language:Chinese
-
Abstract:
This paper explored the chemical constituents of Boswellia carterii by column chromatography on silica gel, Sephadex LH-20, ODS column chromatography, and semi-preparative HPLC. The structures of the compounds were identified by physicochemical properties and spectroscopic data such as infrared radiation(IR), ultra violet(UV), mass spectrometry(MS), and nuclear magnetic resonance(NMR). Seven diterpenoids were isolated and purified from n-hexane of B. carterii. The isolates were identified as(1S,3E,7E,11R,12R)-11-hydroxy-1-isopropyl-4,8,12-trimethyl-15-oxabicyclo[10.2.1]pentadeca-3,7-dien-5-one(1),(1R,3S,4R,7E,11E)-4,8,12,15,15-pentamethyl-14-oxabicyclo[11.2.1]hexadeca-7,11-dien-4-ol(2), incensole(3),(-)-(R)-nephthenol(4), euphraticanoid F(5), dilospirane B(6), and dictyotin C(7). Among them, compounds 1 and 2 were new and their absolute configurations were determined by comparison of the calculated and experimental electronic circular dichroisms(ECDs). Compounds 6 and 7 were obtained from B. carterii for the first time.
