Research advance on structure and function of amides in Zanthoxylum plants.
10.19540/j.cnki.cjcmm.20230120.201
- Author:
Qian-Nv YE
1
;
Xiao-Feng SHI
2
;
Jun-Li YANG
3
Author Information
1. College of Pharmacy, Gansu University of Chinese Medicine Lanzhou 730000, China.
2. College of Pharmacy, Gansu University of Chinese Medicine Lanzhou 730000, China Institute of Materia Medica, Gansu Provincial Academic Institute for Medical Research Lanzhou 730000, China.
3. Key Laboratory of Chemistry of Northwestern Plant Resources, CAS, Key Laboratory for Natural Medicines of Gansu Province,Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences Lanzhou 730000, China.
- Publication Type:Journal Article
- Keywords:
Zanthoxylum;
amides;
molecular structure;
pharmacological activity
- MeSH:
Zanthoxylum/chemistry*;
Amides/chemistry*;
Plant Extracts/pharmacology*;
China
- From:
China Journal of Chinese Materia Medica
2023;48(9):2406-2418
- CountryChina
- Language:Chinese
-
Abstract:
Zanthoxylum belongs to the Rutaceae family, and there are 81 Zanthoxylum species and 36 varieties in China. Most of the Zanthoxylum plants are used as culinary spice. In recent years, scholars in China and abroad have carried out in-depth research on Zanthoxylum plants, and found that the peculiar numbing sensation of Zanthoxylum plants originates from amides. It is also determined that amides are an important material basis for exerting pharmacological effects, especially in anti-inflammatory analgesia, anesthesia and other aspects. In this paper, 123 amides in 26 Zanthoxylum plants and their pharmacological activity that have been reported were summarized, which provided scientific reference for the clinical application of Zanthoxylum plants and the research and development of new drugs, and also facilitated the sustainable development and utilization of Zanthoxylum plant resources.
