Progress in Application of Concentrated Growth Factor in Oral Tissue Regeneration.
10.3881/j.issn.1000-503X.15219
- Author:
Ying LU
1
;
Si-Jun WANG
1
;
Duo-Hong ZOU
2
Author Information
1. Department of Stomatology,Affiliated Hospital of Shaoxing University,Shaoxing,Zhejiang 312000,China.
2. College of Stomatology,National Center for Stomatology,Department of Oral Surgery,Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine,Shanghai 200011,China.
- Publication Type:Journal Article
- Keywords:
concentrated growth factor;
oral tissue;
repair and regeneration
- MeSH:
Platelet-Rich Plasma/metabolism*;
Platelet-Rich Fibrin;
Cell Proliferation;
Bone and Bones;
Intercellular Signaling Peptides and Proteins/metabolism*;
Bone Regeneration
- From:
Acta Academiae Medicinae Sinicae
2023;45(3):500-505
- CountryChina
- Language:Chinese
-
Abstract:
Tissue regeneration is an important engineering method for the treatment of oral soft and hard tissue defects.Growth factors,as one of the three elements of tissue regeneration,are a necessary condition for tissue regeneration.Concentrated growth factor(CGF)is a new generation of blood extract prepared by changing the centrifugal speed on the basis of the preparation of platelet-rich plasma(PRP)and platelet-rich fibrin(PRF).It contains abundant growth factors and a fibrin matrix with a three-dimensional network structure,being capable of activating angiogenesis and promoting tissue regeneration and healing.CGF has been widely used in the repair and regeneration of oral soft and hard tissues.This paper introduces the preparation and composition of CGF and reviews the application of CGF in oral implantation and the regeneration of oral bone tissue,periodontal tissue,and dental pulp tissue.
