Recent progress in the biosynthesis of dicarboxylic acids, a monomer of biodegradable plastics.

Rui Zhi; Yanbo LU; Min Wang; Guohui LI; Yu Deng

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Recent progress in the biosynthesis of dicarboxylic acids, a monomer of biodegradable plastics.

Author: Rui ZHI ¹ ; Yanbo LU ² ; Min WANG ² ; Guohui LI ¹ ; Yu DENG ¹
Author Information

1. National Engineering Research Center of Cereal Fermentation and Food Biomanufacturing, Jiangnan University, Wuxi 214122, Jiangsu, China.
2. Shandong Provincial Key Laboratory of Fat & Oil Deep-Processing, Shandong Bohi Industry Co., Ltd., Binzhou, 256500, Shandong, China.
Publication Type:Journal Article
Keywords: biodegradable plastics; dicarboxylic acids; metabolic engineering
MeSH: Biodegradable Plastics; Dicarboxylic Acids; Polymers/metabolism*; Biodegradation, Environmental; Metabolic Engineering
From: Chinese Journal of Biotechnology 2023;39(5):2081-2094
CountryChina
Language:Chinese
Abstract: Plastics are one of the most important polymers with huge global demand. However, the downsides of this polymer are that it is difficult to degrade, which causes huge pollution. The environmental-friendly bio-degradable plastics therefore could be an alternative and eventually fulfill the ever-growing demand from every aspect of the society. One of the building blocks of bio-degradable plastics is dicarboxylic acids, which have excellent biodegradability and numerous industrial applications. More importantly, dicarboxylic acid can be biologically synthesized. Herein, this review discusses the recent advance on the biosynthesis routes and metabolic engineering strategies of some of the typical dicarboxylic acids, in hope that it will help to provide inspiration to further efforts on the biosynthesis of dicarboxylic acids.