Porcine skeletal muscle development regulated by MicroRNA: a review.

Author: Yulin HE ¹ ; Jianjun JIN ¹ ; Dong LI ¹ ; Gongshe YANG ¹ ; Taiyong YU ¹
Author Information

1. College of Animal Science and Technology, Northwest A & F University, Yangling 712100, Shaanxi, China.
Publication Type:Journal Article
Keywords: developmental regulation; miRNA; pig; skeletal muscle
MeSH: Swine; Animals; MicroRNAs/metabolism*; Muscle, Skeletal/metabolism*; Muscle Development/genetics*
From: Chinese Journal of Biotechnology 2023;39(4):1514-1524
CountryChina
Language:Chinese
Abstract: The growth and development of skeletal muscle is an important factor affecting pork production and quality, which is elaborately regulated by many genetic and nutritional factors. MicroRNA (miRNA) is a non-coding RNA with a length of about 22 nt, which binds to the 3'UTR sequence of the mRNA of the target genes, and consequently regulates its post-transcriptional expression level. In recent years, a large number of studies have shown that miRNAs are involved in various life processes such as growth and development, reproduction, and diseases. The role of miRNAs in the regulation of porcine skeletal muscle development was reviewed, with the hope to provide a reference for the genetic improvement of pigs.