Frailty in kidney transplant candidates and recipients: pathogenesis and intervention strategies.
10.1097/CM9.0000000000002312
- Author:
Huawei CAO
1
;
Jiandong ZHANG
2
;
Zejia SUN
1
;
Jiyue WU
1
;
Changzhen HAO
1
;
Wei WANG
1
Author Information
1. Department of Urology, Beijing Chao-yang Hospital, Capital Medical University, Beijing 100020, China.
2. Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital, Third Hospital of Shanxi Medical University, Taiyuan, Shanxi 030032, China.
- Publication Type:Journal Article
- MeSH:
Humans;
Frailty/epidemiology*;
Risk Factors;
Quality of Life;
Kidney Failure, Chronic;
Kidney Transplantation/adverse effects*;
Cross-Sectional Studies;
Transplant Recipients
- From:
Chinese Medical Journal
2023;136(9):1026-1036
- CountryChina
- Language:English
-
Abstract:
With the rapid aging of the global population posing a serious problem, frailty, a non-specific state that reflects physiological senescence rather than aging in time, has become more widely addressed by researchers in various medical fields. A high prevalence of frailty is found among kidney transplant (KT) candidates and recipients. Therefore, their frailty has become a research hotspot in the field of transplantation. However, current studies mainly focus on the cross-sectional survey of the incidence of frailty among KT candidates and recipients and the relationship between frailty and transplantation. Research on the pathogenesis and intervention is scattered, and relevant review literature is scarce. Exploring the pathogenesis of frailty in KT candidates and recipients and determining effective intervention measures may reduce waiting list mortality and improve the long-term quality of life of KT recipients. Therefore, this review explains the pathogenesis and intervention measures for frailty in KT candidates and recipients to provide a reference for the formulation of effective intervention strategies.
