Observation of effects of the brain-located mild hypothermia therapy on acute progressive cerebral infarction
- VernacularTitle:头颅局部亚低温治疗急性进展性脑梗死临床研究
- Author:
Shiwen ZHU
;
Qinghua REN
;
Yizhao LI
;
Chengzhong SONG
;
Yuanbiao SUN
- Publication Type:Journal Article
- Keywords:
located mild hypothermia, acute progressive cerebral infarction, treatment
- From:
Chinese Journal of Rehabilitation Theory and Practice
2003;9(6):326-327
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo study effects of treating acute progressive cerebral infarction by the brain-located mild hypothermia therapy.Methods60 patients were randomly divided into the treatment group (30 cases) and the control group (30 cases). Drugs were used in both groups, and the located mild hypothermia therapy was only applied in the treatment group. After 72 hours and 7 days, the volume of cerebral infarction and the nerve function deficiency (NFD) scores of hemiplegic limbs were compared.ResultsThe volume of cerebral infarction of the treatment group was significantly smaller than that of the control group (P<0.01).There were significant differences on the neurological impairment scores between two groups (P<0.01).Conclusions The brain-located mild hypothermia therapy can reduce hydrocephalus of patients with acute progressive cerebral infarction, and have brain protection. These results provide an important theoretical foundation for the treatment of cerebral infraction with low-temperature therapy.