Effect of electroacupuncture on vascular dementia and AVP in brain of rats
- VernacularTitle:电针对高血压血管性痴呆大鼠的疗效及对脑AVP的影响
- Author:
Fei-zhi MO
;
Jian-qiang LI
;
Zhao-hui CHEN
;
Xinsheng LAI
;
Jiawei ZHANG
- Publication Type:Journal Article
- Keywords:
vascular dementia, acupuncture, electoracupuncture, water maze, arginine vasopressin(AVP), animal, experiment
- From:
Chinese Journal of Rehabilitation Theory and Practice
2002;8(3):129-131
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo probe the effect of the electroacupuncture on vascular dementia(VD) and content of arginine vasopressin(AVP) in brain of rats. Methods30 Sprague Dawley rats were made renal hypertension(RHR) by the kidney arteries pinched with silver clip.After 42 days, their bilateral common carotid arteries were blocked repeatedly to cause cerebral ischemia.The Hypertension Vascular Dementia model was made. Then they were divided into model group,electroacupuncture group and medicine group(Dihydroergotoxine,DHET) with 10 in each group. The course was 28 days. The ability of learning and memorizing was observed by water maze, and the content of AVP in brain was detected after treatment. ResultsThe latent period of the electroacupuncture group and medicine group was shorter than that of the model group(P<0.05-0.005), and that of the electroacupuncture group was shorter than medicine group(P<0.05-0.005). In frontal lobe, the contents of AVP in the electroacupuncture and medicine groups were higher than that of model group( P<0.01,P<0.05), and the electroacupuncture group was higher than medicine group in striatum (P<0.05). Conclusions It indicated that electroacupuncture therapy can promote the ability of learning and memorizing and enhance the content of AVP in the brain of VD rats. It's therapeutic effect is better than that of DHET.
