Repair sciatic nerve gap of the rats with novel artifical nerve guide
- VernacularTitle:借助人工神经修复大鼠坐骨神经缺损的实验研究
- Author:
Zhaoyang YANG
;
Qing CAI
;
Qiang LU
;
Man JI
;
Yuanshen WANG
;
Erjing GAO
;
Yujun LIU
;
Xiaoguang LI
- Publication Type:Journal Article
- Keywords:
the artifical nerve, nerve regeneration, sciatic nerve, rats
- From:
Chinese Journal of Rehabilitation Theory and Practice
2003;9(3):182-183
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo explore the possibility of repairing sciatic nerve gap of rats with artifical nerve graft.MethodsA novel artifical nerve guide was developed and used to suture the 15 milimeter long right sciatic nerve gap of 10 rats, other 7 rats were the control with the right sciatic nerve gap alone.2 and 4 monthes after operation, immunohistochemistry, Osmium staining, Bodian staining,motor end plate staining,WGA-HRP stain tracing have been done to observe the effect of repairing.Results2 months after operations, the sciatic nerve gap were repaired by the regeneration nerve.There was not evident inflammation in the defects.ConclusionsThe artifical nerve graft can induce the nerve to regenerate.
