Neonatal cholestasis secondary to congenital syphilis
- Author:
April P. Padua-Zamora
1
;
Ma. Patricia Riego de Dios
2
;
Germana Emerita V. Gregorio
2
Author Information
- Publication Type:Case Reports
- Keywords: rapid plasma reagin
- MeSH: Congenital syphilis; neonatal cholestasis
- From: Acta Medica Philippina 2023;57(1):62-67
- CountryPhilippines
- Language:English
- Abstract: We report two infants with neonatal cholestasis and hepatosplenomegaly secondary to congenital syphilis. The onset of jaundice of the first infant was at six weeks of life and the second case on the 28th hour of life with associated neurologic and bone involvement. The diagnosis was suspected based on a maternal history of untreated syphilis, clinical findings, and a reactive rapid plasma reagin. Early recognition and treatment can lead to clinical improvement but prevention by mandatory testing and treatment of maternal syphilis is a more effective strategy
- Full text:Neonatal Cholestasis Secondary to Congenital Syphilis.pdf
