The Technique of Intravenous Ketamine Infusion on PostOperative Hyperalgesia in Gluteal Sarcoma
- Author:
Kamaruddin Ibrahim
1
;
Mohd Zulfakar Mazlan
1
Author Information
- Publication Type:Case Reports
- Keywords: Ketamine, Post-Operative Hyperalgesia (POH), N-Methyl-DE Aspartate Receptor (NMDAR)
- From:Malaysian Journal of Medicine and Health Sciences 2021;17(No.4):437-438
- CountryMalaysia
- Language:English
- Abstract: Post-Operative Hyperalgesia (POH) is an uncommon painful condition suffered after surgery. It is poorly identified and usually needs a large dose of strong opioids administration to attenuate pain. Primarily POH originated from the activation of N-Methyl-DE Aspartate Receptor (NMDAR) located at the spinal cord. Hence NMDAR antagonist (ketamine) may inhibit this pain mechanism leading to desirable post-operative pain relief. We presented a case report on how to recognize POH, initiated ketamine infusion, and its limitation. We found ketamine therapy reduced opioid requirements and drastically improve patient daily bed activities.
- Full text:11.2021my1171.pdf
