A Case of Severe Transient Sinus Bradycardia in Herpes Simplex  Infection

Wan Muhammad Najib Wan Mahmud Sabri; Nor Azni Yahaya; Amelia Alias; Muhamad Azamin Anuar

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A Case of Severe Transient Sinus Bradycardia in Herpes Simplex Infection

Author: Wan Muhammad Najib Wan Mahmud Sabri ^{1
,

2} ; Nor Azni Yahaya ¹ ; Amelia Alias ¹ ; Muhamad Azamin Anuar ^{1
,

3}
Author Information

1. Department of Paediatrics, Hospital Raja Perempuan Zainab II, Kota Bharu, Kelantan, Malaysia&
2. Department of Paediatrics, Kampus Kesihatan, Universiti Sains Malaysia, Kubang Kerian, 16150 Kota Bharu, Kelantan, Malaysia
3. Department of Paediatrics, Kulliyyah of Medicine, International Islamic University Malaysia, 25200 Kuantan, Pahang, Malaysia
Publication Type:Case Reports
Keywords: Herpes simplex, HSV infection, Herpes infection, Sinus bradycardia, Arrhythmia
From:Malaysian Journal of Medicine and Health Sciences 2021;17(No.4):428-430
CountryMalaysia
Language:English
Abstract: Herpes simplex virus remains the commonest organism of sporadic encephalitis. Common presentations in herpes simplex encephalitis are seizures and behavioural changes apart from fever, lethargy and headache. Cardiac manifestations, nonetheless, are uncommon in herpes simplex infection. We presented an 8-year-old boy with clinical meningoencephalitis and bradycardia. The initial impression was typhoid meningitis due to severe bradycardia. He was managed in paediatric intensive care unit with transcutaneous cardiac pacemaker and infusion of low dose noradrenaline until the bradycardia resolved. A diagnosis of herpes simplex encephalitis was made based on clinical and specific right temporal and focal radiological findings including right insular ribbon involvement, focal changes over temporal and frontal electroencephalographic (EEG) inference and positive HSV IgM serological confirmation.
Full text:11.2021my1168.pdf