Biosafety risks and mitigation strategies for mosquito infection in Arthropod Containment Level-2 laboratory
- Author:
YANG Ci-han
;
WU Qun
;
WANG Fei
;
HE Chang-hua
;
YUAN Zhi-ming
;
XIA Han
- Publication Type:Journal Article
- Keywords:
Arthropod-borne diseases;
arthropod containment level-2 laboratory;
mosquito vector;
biosafety risk
- From:
China Tropical Medicine
2023;23(4):420-
- CountryChina
- Language:Chinese
-
Abstract:
Arthropods of medical importance such as mosquitoes, ticks and sandflies are one of the key drivers of arthropod-borne diseases outbreak, posing a great threat to global public health security. For further understanding the transmission mechanisms of arthropod-borne diseases and establishing the prevention and control measures, a series of experiments of arthropods infection need to be carried out under laboratory conditions. Besides the regular biosafety requirements, some specific considerations need to be taken into account when performing arthropod infection and the infected arthropod rearing. Except for the physical containment composed of biosafety facilities, a comprehensive assessment of the biosafety risks during operations and corresponding preventive measures are also critical to eliminate or mitigate the biosafety risks. In this paper, we introduce our practice in handling mosquito infection with Risk Group 2 pathogens in Arthropod Containment Level-2 (ACL-2) laboratory, with an aim to provide a reference for researchers in related fields.
- Full text:19.Biosafety risks and mitigation strategies for mosquito infection in Arthropod Containment Level-2 laboratory.pdf
