Anesthetic management in bilateral deep brain stimulation for X-linked Dystonia Parkinsonism: Early single institution experience from the Philippines
https://doi.org/10.47895/amp.v54i2.1543
- Author:
Mary Ellen Chiong-Perez
1
,
2
;
Cid Czarina E. Diesta
2
;
Jean Quint L. Oropilla
2
Author Information
1. Department of Anesthesiology, College of Medicine and Philippine General Hospital, University of the Philippines Manila
2. Asian Hospital and Medical Center
- Publication Type:Journal Article
- Keywords:
X-linked dystonia-parkinsonism;
Anesthetic management
- MeSH:
Deep Brain Stimulation
- From:
Acta Medica Philippina
2020;54(2):203-209
- CountryPhilippines
- Language:English
-
Abstract:
X-linked dystonia-parkinsonism (XDP) is a rare, adult-onset, progressive, hereditary neurological movement disorder primarily affecting Filipino men with maternal families from Panay province of the Philippines. Medical treatment modalities currently being used have offered temporary symptomatic relief. Surgical management in the form of bilateral globus pallidi internae (Gpi) deep brain stimulation (DBS) has shown promising results and is increasingly being performed in advanced centers, as reported in international literature. Presented herein is the local experience of seven (7) retrospectively reviewed cases from February 2018 to February 2019 in a tertiary center in the Philippines with a particular focus on anesthetic management. All patients were male, from Panay, and presented with progressive dystonia and parkinsonism. All patients underwent planned bilateral, simultaneous DBS electrode, and implantable pulse generator (IPG) placement performed by a multidisciplinary team. Anesthetic management consisted of Bispectral Index (BIS) guided conscious sedation with low dose propofol and remifentanil infusions with a complete scalp nerve block (SB) at the start of the procedure then shifted to awake monitored anesthesia care during electrode placement, microelectrode recording (MER) and macro stimulation testing. All were put under general anesthesia with a supraglottic airway device during the placement of the internal pulse generator (IPG) in the infraclavicular area. All seven patients had successful localization, and insertion of the DBS electrode and discharged improved. The anesthetic management of the DBS used in these cases warrants further investigation and may lead to standardization of future practice.
- Full text:1543-Article Text-7063-1-10-20200430.pdf
