A ten-year retrospective study on the clinical features and outcomes of Pediatric Intestinal Tuberculosis admitted in UP-Philippine General Hospital
https://doi.org/10.47895/amp.v54i2.1522
- Author:
Eleonor G. Rodenas-Sabico
1
;
Germana Emerita V. Gregorio
1
;
Ma. Liza Antoinette M. Gonzales
1
Author Information
1. Department of Pediatrics, College of Medicine and Philippine General Hospital, University of the Philippines Manila
- Publication Type:Journal Article
- Keywords:
Intestinal tuberculosis
- MeSH:
Tuberculosis, Extrapulmonary;
Mycobacterium tuberculosis
- From:
Acta Medica Philippina
2020;54(2):128-133
- CountryPhilippines
- Language:English
-
Abstract:
Objective:To describe the clinical, biochemical, microbiologic, radiologic and histological features and outcome of intestinal TB.
Methods:Medical records of patients diagnosed with intestinal TB were reviewed. Cases were considered bacteriologically-confirmed if intestinal tissue was positive on smear culture or polymerase chain reaction (PCR); and clinically-diagnosed if with clinical, histologic, and radiologic evidence of extra-pulmonary TB.
Results:Fifteen patients [Mean (SD) age: 13 (4) years; 53% females] were included. One was bacteriologically-confirmed; and fourteen were clinically-diagnosed. Fever (87%) and abdominal pain (73%) were commonly seen. Seven (47%) had anemia, 5 (33%) leukocytosis and 10 (71%) hypoalbuminemia. Eleven (73%) were positive on smear or TB PCR of various specimens. Nine of 10 (90%) patients with an abdominal CT scan had thickening of bowel loops. Three with intestinal biopsy demonstrated caseation granuloma. Fourteen patients were given quadruple anti-TB medications. Six had surgery, 8 had no disease-related complications, 4 died of sepsis and 3 were lost to follow up.
Conclusion:Intestinal TB presents with non-specific clinical and laboratory features. Radiologic findings may provide a clue to the diagnosis. Histologic confirmation in intestinal tissue was only seen in a few cases. The prognosis was favorable for patients who completed the anti-TB treatment.
- Full text:1522-Article Text-6982-1-10-20200430.pdf
