Application of molecular markers in the research of genetic diversity in medical helminths
- Author:
XU Fang-fang
;
SU Xiao-yi
;
LONG Shao-rong
;
LIU Ruo-dan
;
JIANG Peng
;
GUI Jing
;
WANG Zhong-quan
;
ZHANG Xi
- Publication Type:Review
- Keywords:
Molecular marker;
genetic diversity;
cestoda;
trematoda;
nematoda
- From:
China Tropical Medicine
2023;23(1):83-
- CountryChina
- Language:Chinese
-
Abstract:
Human-animal parasitic diseases caused by medical helminths are hazardous to human health. Genetic polymorphism studies on medical helminth populations can not only understand the biological characteristics and genetic structure of their populations, but also help reveal how they adapt to their parasitic environment, thus contributing to deepen our understanding of the epidemiological patterns of parasitic diseases and improve our understanding of accurate prevention and control of parasitic diseases. With the development of molecular biology, molecular markers such as DNA barcodes, simple sequence repeats, and single nucleotide polymorphism markers have been widely used to study the genetic relationships among parasite populations and individuals, and to reveal the genetic variation of parasite populations and the evolution of species origins. In this paper, we systematically review the application of three molecular markers commonly used in the study of genetic polymorphism in medical helminths, with a view to laying the foundation for related research.
- Full text:15.Application of molecular markers in the research of genetic diversity in medical helminths.pdf