Research progress of research on the effect of quorum-sensing system on periodontal pathogens
10.13591/j.cnki.kqyx.2023.03.015
- VernacularTitle:群体感应系统对牙周致病菌影响的研究进展
- Author:
Dexu WANG
1
;
Xiaojie LUO
;
Xiaotao CHEN
Author Information
1. Xinjiang Medical University, Urumqi 830002, China
- Publication Type:Review
- Keywords:
quorum-sensing;
quorum-sensing inhibitors;
periodontitis
- From:
STOMATOLOGY
2023;43(3):267-272
- CountryChina
- Language:Chinese
-
Abstract:
Periodontitis is one of the most common oral diseases in humans. As the initiating factor of periodontitis, dental plaque bacteria, is the primary factor leading to periodontitis. Quorum-sensing system relies on quorum-sensing signaling molecules to regulate and strengthenthe communication between different kinds of bacteria, strengthen the communication between bacteria, and promote the occurrence and development of diseases. Quorum-sensing system also plays an important role in promoting the formation of dental plaque biofilm by dental plaque bacteria. In recent years, many studies have shown that quorum-sensing inhibitors can effectively attenuate quorum sensing between bacteria and inhibit and reduce the formation of plaque biofilms between bacteria and the expression of their virulence factors. In this paper, we will review the progress of research on the effects of quorum-sensing signaling molecules on periodontitis pathogens.
